μ-Crystallin in Mouse Skeletal Muscle Promotes a Shift from Glycolytic toward Oxidative Metabolism

μ-Crystallin in Mouse Skeletal Muscle Promotes a Shift from Glycolytic toward Oxidative Metabolism

μ-Crystallin, encoded by the CRYM gene, binds the thyroid hormones, T3 and T4. Because T3 and T4 are potent regulators of metabolism and gene expression, and CRYM levels in human skeletal muscle can vary widely, we investigated the effects of overexpression of Crym. We generated transgenic mice, Cry...

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Bibliographic Details
Main Authors: Christian J. Kinney, Andrea O'Neill, Kaila Noland, Weiliang Huang, Joaquin Muriel, Valeriy Lukyanenko, Maureen A. Kane, Christopher W. Ward, Alyssa F. Collier, Joseph A. Roche, John C. McLenithan, Patrick W. Reed, Robert J. Bloch
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Current Research in Physiology
Subjects:
Glycolysis
β-oxidation
RER
RNA-seq
Proteomics
Thyroid hormone
Online Access:http://www.sciencedirect.com/science/article/pii/S2665944121000079

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http://www.sciencedirect.com/science/article/pii/S2665944121000079

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