A low cartilage formation and repair endotype predicts radiographic progression of symptomatic knee osteoarthritis

A low cartilage formation and repair endotype predicts radiographic progression of symptomatic knee osteoarthritis

Abstract Background Osteoarthritis (OA) is a disease with multiple endotypes. A hallmark of OA is loss of cartilage; however, it is evident that the rate of cartilage loss differs among patients, which may partly be attributed to differential capacity for cartilage repair. We hypothesize that a low...

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Bibliographic Details
Main Authors: Yunyun Luo, Jonathan Samuels, Svetlana Krasnokutsky, Inger Byrjalsen, Virginia B. Kraus, Yi He, Morten A. Karsdal, Steven B. Abramson, Mukundan Attur, Anne C. Bay-Jensen
Format: Article
Language:English
Published: SpringerOpen 2021-03-01
Series:Journal of Orthopaedics and Traumatology
Subjects:
Cartilage biomarker
Extracellular matrix
Joint space narrowing
Knee osteoarthritis
Matrix synthesis
Online Access:https://doi.org/10.1186/s10195-021-00572-0

Internet

https://doi.org/10.1186/s10195-021-00572-0

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