The interaction of schizophrenia-related proteins DISC1 and NDEL1, in light of the newly identified domain structure of DISC1

DISC1 and NDEL1 are both key proteins in cortical neurodevelopment, which are each also implicated in the pathogenesis of mental illness. That the two proteins interact with each other in a functionally important manner is well established, but two distinct binding domains for NDEL1 on DISC1 have be...

Full description

Bibliographic Details
Main Author: Nicholas J. Bradshaw
Format: Article
Language:English
Published: Taylor & Francis Group 2017-07-01
Series:Communicative & Integrative Biology
Subjects:
Online Access:http://dx.doi.org/10.1080/19420889.2017.1335375