Peripheral blood transcriptomic sub-phenotypes of pediatric acute respiratory distress syndrome

Peripheral blood transcriptomic sub-phenotypes of pediatric acute respiratory distress syndrome

Abstract Background Acute respiratory distress syndrome (ARDS) is heterogeneous and may be amenable to sub-phenotyping to improve enrichment for trials. We aimed to identify subtypes of pediatric ARDS based on whole blood transcriptomics. Methods This was a prospective observational study of childre...

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Bibliographic Details
Main Authors: Nadir Yehya, Brian M. Varisco, Neal J. Thomas, Hector R. Wong, Jason D. Christie, Rui Feng
Format: Article
Language:English
Published: BMC 2020-12-01
Series:Critical Care
Subjects:
Children
ARDS
PARDS
Endotypes
Gene expression
Sub-phenotypes
Online Access:https://doi.org/10.1186/s13054-020-03410-7

Internet

https://doi.org/10.1186/s13054-020-03410-7

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