ChIP-chip versus ChIP-seq: Lessons for experimental design and data analysis

<p>Abstract</p> <p>Background</p> <p>Chromatin immunoprecipitation (ChIP) followed by microarray hybridization (ChIP-chip) or high-throughput sequencing (ChIP-seq) allows genome-wide discovery of protein-DNA interactions such as transcription factor bindings and histone...

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Bibliographic Details
Main Authors: Karchenko Peter V, Bishop Eric, Ho Joshua WK, Nègre Nicolas, White Kevin P, Park Peter J
Format: Article
Language:English
Published: BMC 2011-02-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/12/134