Old Maids: Aging and Its Impact on Microglia Function

Microglia are highly active and vigilant housekeepers of the central nervous system that function to promote neuronal growth and activity. With advanced age, however, dysregulated inflammatory signaling and defects in phagocytosis impede their ability to perform the most essential of homeostatic fun...

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Bibliographic Details
Main Authors: Edward C. Koellhoffer, Louise D. McCullough, Rodney M. Ritzel
Format: Article
Language:English
Published: MDPI AG 2017-04-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/18/4/769