Non-invasive Drug Monitoring of β-Lactam Antibiotics Using Sweat Analysis—A Pilot Study

Non-invasive Drug Monitoring of β-Lactam Antibiotics Using Sweat Analysis—A Pilot Study

Background: Antimicrobial resistance is a major challenge in treating infectious diseases. Therapeutic drug monitoring (TDM) can optimize and personalize antibiotic treatment. Previously, antibiotic concentrations in tissues were extrapolated from skin blister studies, but sweat analyses for TDM hav...

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Bibliographic Details
Main Authors: Noé Brasier, Andreas Widmer, Michael Osthoff, Markus Mutke, Fiorangelo De Ieso, Pascale Brasier-Lutz, Lisa Wolfe, Vikas Aithal, Corey D. Broeckling, Jessica Prenni, Jens Eckstein
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Medicine
Subjects:
sweat
therapeutic drug monitoring
antimicrobial resistance
antibiotics
cefepime
imipenem
Online Access:https://www.frontiersin.org/article/10.3389/fmed.2020.00476/full

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https://www.frontiersin.org/article/10.3389/fmed.2020.00476/full

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