Position- and Time-Dependent Arc Expression Links Neuronal Activity to Synaptic Plasticity During Epileptogenesis

Position- and Time-Dependent Arc Expression Links Neuronal Activity to Synaptic Plasticity During Epileptogenesis

In mesial temporal lobe epilepsy (mTLE) an initial precipitating injury can trigger aberrant wiring of neuronal circuits causing seizure activity. While circuit reorganization is known to be largely activity-dependent, the interactions between neuronal activity and synaptic plasticity during the dev...

Full description

Bibliographic Details
Main Authors: Philipp Janz, Pascal Hauser, Katharina Heining, Sigrun Nestel, Matthias Kirsch, Ulrich Egert, Carola A. Haas
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Cellular Neuroscience
Subjects:
hippocampus
epilepsy
seizure
kainate
Arg3.1
spine
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2018.00244/full

Internet

https://www.frontiersin.org/article/10.3389/fncel.2018.00244/full

Similar Items