Expression of human apolipoprotein A-II in apolipoprotein E-deficient mice induces features of familial combined hyperlipidemia

Expression of human apolipoprotein A-II in apolipoprotein E-deficient mice induces features of familial combined hyperlipidemia

Familial combined hyperlipidemia (FCHL) is a common inherited hyperlipidemia and a major risk factor for atherothrombotic cardiovascular disease. The cause(s) leading to FCHL are largely unknown, but the existence of unidentified “major” genes that would increase VLDL production and of “modifier” ge...

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Bibliographic Details
Main Authors: Joan Carles Escolà-Gil, Josep Julve, Àfrica Marzal-Casacuberta, Jordi Ordóñez-Llanos, Francesc González-Sastre, Francisco Blanco-Vaca
Format: Article
Language:English
Published: Elsevier 2000-08-01
Series:Journal of Lipid Research
Subjects:
apoB
atherosclerosis
high density lipoprotein
transgenic mice
very low density lipoprotein
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520334416

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http://www.sciencedirect.com/science/article/pii/S0022227520334416

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