Repair of DNA Double-Strand Breaks in Heterochromatin

DNA double-strand breaks (DSBs) are among the most damaging lesions in DNA, since, if not identified and repaired, they can lead to insertions, deletions or chromosomal rearrangements. DSBs can be in the form of simple or complex breaks, and may be repaired by one of a number of processes, the natur...

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Bibliographic Details
Main Author: Felicity Z. Watts
Format: Article
Language:English
Published: MDPI AG 2016-12-01
Series:Biomolecules
Subjects:
HP1
Online Access:http://www.mdpi.com/2218-273X/6/4/47