Rapid screening for individualized chemotherapy optimization of colorectal cancer: A novel conditional reprogramming technology-based functional diagnostic assay.

Rapid screening for individualized chemotherapy optimization of colorectal cancer: A novel conditional reprogramming technology-based functional diagnostic assay.

Background: In vitro patient tumor models such as patient-derived organoids (PDO) and conditionally reprogrammed (CR) cell culture are important for translational research and pre-clinical drug testing. In this study we present a personalized drug sensitivity test for late stage, potentially operabl...

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Bibliographic Details
Main Authors: Yingjie Li, Dagang Guo, Yihong Zhang, Lin Wang, Tingting Sun, Zhongwu Li, Xiaoyan Zhang, Shuai Wang, Yiyou Chen, Aiwen Wu
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Translational Oncology
Subjects:
Conditional reprogramming
Colorectal cancer
Chemotherapy
Pre-clinical
In vitro drug test
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523320304277

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http://www.sciencedirect.com/science/article/pii/S1936523320304277

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