Myosin-Va-dependent cell-to-cell transfer of RNA from Schwann cells to axons.

Myosin-Va-dependent cell-to-cell transfer of RNA from Schwann cells to axons.

To better understand the role of protein synthesis in axons, we have identified the source of a portion of axonal RNA. We show that proximal segments of transected sciatic nerves accumulate newly-synthesized RNA in axons. This RNA is synthesized in Schwann cells because the RNA was labeled in the co...

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Bibliographic Details
Main Authors: José R Sotelo, Lucía Canclini, Alejandra Kun, José R Sotelo-Silveira, Lei Xu, Horst Wallrabe, Aldo Calliari, Gonzalo Rosso, Karina Cal, John A Mercer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3633983?pdf=render

Internet

http://europepmc.org/articles/PMC3633983?pdf=render

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