Impact of Single-Nucleotide Polymorphisms of <i>CTLA-4</i>, <i>CD80</i> and <i>CD86</i> on the Effectiveness of Abatacept in Patients with Rheumatoid Arthritis

Impact of Single-Nucleotide Polymorphisms of <i>CTLA-4</i>, <i>CD80</i> and <i>CD86</i> on the Effectiveness of Abatacept in Patients with Rheumatoid Arthritis

Abatacept (ABA) is used as a first-line treatment in patients diagnosed with moderate and severe rheumatoid arthritis (RA). The interindividual response to ABA therapy is very variable in these patients. The objective of our study was therefore to investigate the role of polymorphisms of the <i&g...

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Bibliographic Details
Main Authors: Noelia Marquez Pete, María del Mar Maldonado Montoro, Cristina Pérez Ramírez, Almudena Sánchez Martín, Juan Enrique Martínez de la Plata, Fernando Martínez Martínez, Rafael Caliz Caliz, Abdelali Daddaoua, María del Carmen Ramírez Tortosa, Alberto Jiménez Morales
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Journal of Personalized Medicine
Subjects:
rheumatoid arthritis
abatacept
CTLA4
effectiveness
polymorphisms
Online Access:https://www.mdpi.com/2075-4426/10/4/220

Internet

https://www.mdpi.com/2075-4426/10/4/220

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