cGMP and NHR signaling co-regulate expression of insulin-like peptides and developmental activation of infective larvae in Strongyloides stercoralis.

The infectious form of the parasitic nematode Strongyloides stercoralis is a developmentally arrested third-stage larva (L3i), which is morphologically similar to the developmentally arrested dauer larva in the free-living nematode Caenorhabditis elegans. We hypothesize that the molecular pathways r...

Full description

Bibliographic Details
Main Authors: Jonathan D Stoltzfus, Stephen M Bart, James B Lok
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-07-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4092141?pdf=render