Multi-Omics Integrative Bioinformatics Analyses Reveal Long Non-coding RNA Modulates Genomic Integrity via Competing Endogenous RNA Mechanism and Serves as Novel Biomarkers for Overall Survival in Lung Adenocarcinoma

Multi-Omics Integrative Bioinformatics Analyses Reveal Long Non-coding RNA Modulates Genomic Integrity via Competing Endogenous RNA Mechanism and Serves as Novel Biomarkers for Overall Survival in Lung Adenocarcinoma

Long non-coding RNA (lncRNA) plays a crucial role in modulating genome instability, immune characteristics, and cancer progression, within which genome instability was identified as a critical regulator in tumorigenesis and tumor progression. However, the existing accounts fail to detail the regulat...

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Bibliographic Details
Main Authors: Zhonglin Wang, Ziyuan Ren, Rui Li, Junpeng Ge, Guoming Zhang, Yaodong Xin, Yiqing Qu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
genome instability
lung adenocarcinoma
lncRNA
bioinformatics
ceRNA
prognosis
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.691540/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.691540/full

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