Activation of AMP-Activated Protein Kinase Attenuates Tumor Necrosis Factor-α-Induced Lipolysis via Protection of Perilipin in 3T3-L1 Adipocytes

Activation of AMP-Activated Protein Kinase Attenuates Tumor Necrosis Factor-α-Induced Lipolysis via Protection of Perilipin in 3T3-L1 Adipocytes

BackgroundTumor necrosis factor (TNF)-α and AMP-activated protein kinase (AMPK) are known to stimulate and repress lipolysis in adipocytes, respectively; however, the mechanisms regulating these processes have not been completely elucidated.MethodsThe key factors and mechanism of action of TNF-α and...

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Bibliographic Details
Main Authors: Seok-Woo Hong, Jinmi Lee, Se Eun Park, Eun-Jung Rhee, Cheol-Young Park, Ki-Won Oh, Sung-Woo Park, Won-Young Lee
Format: Article
Language:English
Published: Academya Publishing Co. 2014-12-01
Series:Endocrinology and Metabolism
Subjects:
AMP-activated protein kinases
Lipolysis
Perilipin
PERK/eIF2α
Adipocytes
Online Access:http://e-enm.org/Synapse/Data/PDFData/2008ENM/enm-29-553.pdf

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http://e-enm.org/Synapse/Data/PDFData/2008ENM/enm-29-553.pdf

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