Expression of the memory marker CD45RO on helper T cells in macaques.

In humans it has been reported that a major site of the latent reservoir of HIV is within CD4+ T cells expressing the memory marker CD45RO, defined by the mAb UCHL1. There are conflicting reports regarding the expression of this antigen in macaques, the most relevant animal species for studying HIV...

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Bibliographic Details
Main Authors: Michael Valentine, Kejing Song, Grace A Maresh, Heather Mack, Maria Cecilia Huaman, Patricia Polacino, On Ho, Anthony Cristillo, Hye Kyung Chung, Shiu-Lok Hu, Seth H Pincus
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3762710?pdf=render