Lithium-mediated Ferration of Fluoroarenes

While fluoroaryl fragments are ubiquitous in many pharmaceuticals, the deprotonation of fluoroarenes using organolithium bases constitutes an important challenge in polar organometallic chemistry. This has been widely attributed to the low stability of the in situ generated aryl lithium intermediate...

Full description

Bibliographic Details
Main Authors: Lewis C. H. Maddock, Alan Kennedy, Eva Hevia
Format: Article
Language:deu
Published: Swiss Chemical Society 2020-11-01
Series:CHIMIA
Subjects:
Online Access:https://www.ingentaconnect.com/contentone/scs/chimia/2020/00000074/00000011/art00004