Inert Coats of Magnetic Nanoparticles Prevent Formation of Occlusive Intravascular Co-aggregates With Neutrophil Extracellular Traps

Inert Coats of Magnetic Nanoparticles Prevent Formation of Occlusive Intravascular Co-aggregates With Neutrophil Extracellular Traps

If foreign particles enter the human body, the immune system offers several mechanisms of response. Neutrophils forming the first line of the immune defense either remove pathogens by phagocytosis, inactivate them by degranulation or release of reactive oxygen species or immobilize them by the relea...

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Bibliographic Details
Main Authors: Rostyslav Bilyy, Harald Unterweger, Bianca Weigel, Tetiana Dumych, Solomiya Paryzhak, Volodymyr Vovk, Ziyu Liao, Christoph Alexiou, Martin Herrmann, Christina Janko
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Immunology
Subjects:
neutrophil extracellular traps (NETs)
superparamagnetic iron oxide nanoparticles (SPIONs)
biocompatibility
vascular occlusion
clearance
nanoparticle aggregation
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02266/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.02266/full

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