The Effect of Green and Black Tea Polyphenols on BRCA2 Deficient Chinese Hamster Cells by Synthetic Lethality through PARP Inhibition

The Effect of Green and Black Tea Polyphenols on BRCA2 Deficient Chinese Hamster Cells by Synthetic Lethality through PARP Inhibition

Tea polyphenols are known antioxidants presenting health benefits due to their observed cellular activities. In this study, two tea polyphenols, epigallocatechin gallate, which is common in green tea, and theaflavin, which is common in black tea, were investigated for their PARP inhibitory activity...

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Bibliographic Details
Main Authors: Shaherah Alqahtani, Kelly Welton, Jeffrey P. Gius, Suad Elmegerhi, Takamitsu A. Kato
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:International Journal of Molecular Sciences
Subjects:
theaflavin
epigallocatechin gallate
PARP
BRCA2
synthetic lethality
Online Access:http://www.mdpi.com/1422-0067/20/6/1274

Internet

http://www.mdpi.com/1422-0067/20/6/1274

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