Analysis of chromosomal aberrations and recombination by allelic bias in RNA-Seq

Chromosomal aberrations can be detected by global gene expression analysis. Here, the authors report eSNP-Karyotyping, a new method that can detect chromosomal aberrations by measuring the ratio of expression between the two alleles without comparison to a matched diploid sample.

Bibliographic Details
Main Authors: Uri Weissbein, Maya Schachter, Dieter Egli, Nissim Benvenisty
Format: Article
Language:English
Published: Nature Publishing Group 2016-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms12144