Active Protein Neddylation or Ubiquitylation Is Dispensable for Stress Granule Dynamics

Summary: Stress granule (SG) formation is frequently accompanied by ubiquitin proteasome system (UPS) impairment and ubiquitylated protein accumulation. SGs, ubiquitin, and UPS components co-localize, but the relationship between the ubiquitin pathway and SGs has not been systematically characterize...

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Bibliographic Details
Main Authors: Sebastian Markmiller, Amit Fulzele, Reneé Higgins, Marilyn Leonard, Gene W. Yeo, Eric J. Bennett
Format: Article
Language:English
Published: Elsevier 2019-04-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S221112471930470X