Avirulent Bacillus anthracis Strain with Molecular Assay Targets as Surrogate for Irradiation-Inactivated Virulent Spores

Avirulent Bacillus anthracis Strain with Molecular Assay Targets as Surrogate for Irradiation-Inactivated Virulent Spores

The revelation in May 2015 of the shipment of γ irradiation–inactivated wild-type Bacillus anthracis spore preparations containing a small number of live spores raised concern about the safety and security of these materials. The finding also raised doubts about the validity of the protocols and pro...

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Bibliographic Details
Main Authors: Roger D. Plaut, Andrea B. Staab, Mark A. Munson, Joan S. Gebhardt, Christopher P. Klimko, Avery V. Quirk, Christopher K. Cote, Tony L. Buhr, Rebecca D. Rossmaier, Robert C. Bernhards, Courtney E. Love, Kimberly L. Berk, Teresa G. Abshire, David A. Rozak, Linda C. Beck, Scott Stibitz, Bruce G. Goodwin, Michael A. Smith, Shanmuga Sozhamannan
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2018-04-01
Series:Emerging Infectious Diseases
Subjects:
Bacillus anthracis
select agent excluded strain
recombinant
genetically inactivated
molecular assay
surrogate
Online Access:https://wwwnc.cdc.gov/eid/article/24/4/17-1646_article

Internet

https://wwwnc.cdc.gov/eid/article/24/4/17-1646_article

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