Intramolecular C-H···O Hydrogen Bonding in 1,4-Dihydropyridine Derivatives

Intramolecular C-H···O Hydrogen Bonding in 1,4-Dihydropyridine Derivatives

The diastereotopy of the methylene protons at positions 2 and 6 in 1,4-dihydropiridine derivatives with various substituents has been investigated. NMR spectroscopy and quantum chemistry calculations show that the CH···O intramolecular hydrogen bond is one of the factors amplifying the chemical shif...

Full description

Bibliographic Details
Main Authors: Brigita Cekavicus, Ruslan Muhamadejev, Gunars Duburs, Edvards Liepinsh, Aiva Plotniece, Brigita Vigante, Marina Petrova
Format: Article
Language:English
Published: MDPI AG 2011-09-01
Series:Molecules
Subjects:
1,4-dihydropyridines
bromination
nucleophilic substitution
hydrogen bond
NMR spectra
quantum chemical calculations
Online Access:http://www.mdpi.com/1420-3049/16/9/8041/

Internet

http://www.mdpi.com/1420-3049/16/9/8041/

Similar Items