Study on hydroxyurea response in hemoglobinopathies patients using genetic markers and liquid erythroid cultures

Study on hydroxyurea response in hemoglobinopathies patients using genetic markers and liquid erythroid cultures

Increased expression of fetal hemoglobin (HbF) may ameliorate the clinical course of hemoglobinopathies. Hydroxyurea (HU) is the only inducer approved for the treatment of these diseases able to stimulate HbF production but patients’ response is highly variable indicating the utility of the identifi...

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Bibliographic Details
Main Authors: Serena Sclafani, Alice Pecoraro, Veronica Agrigento, Antonio Troia, Rosario Di Maggio, Massimiliano Sacco, Aurelio Maggio, Elena D'Alcamo, Rosalba Di Marzo
Format: Article
Language:English
Published: PAGEPress Publications 2016-12-01
Series:Hematology Reports
Subjects:
Hydroxyurea
Haemoglobinopathies
Genetic Markers
Liquid Erythroid Cultures
Online Access:http://www.pagepress.org/journals/index.php/hr/article/view/6678

Internet

http://www.pagepress.org/journals/index.php/hr/article/view/6678

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