EGFR Controls Hair Shaft Differentiation in a p53-Independent Manner

Summary: Epidermal growth factor receptor (EGFR) signaling controls skin development and homeostasis in mice and humans, and its deficiency causes severe skin inflammation, which might affect epidermal stem cell behavior. Here, we describe the inflammation-independent effects of EGFR deficiency duri...

Full description

Bibliographic Details
Main Authors: Nicole Amberg, Panagiota A. Sotiropoulou, Gerwin Heller, Beate M. Lichtenberger, Martin Holcmann, Bahar Camurdanoglu, Temenuschka Baykuscheva-Gentscheva, Cedric Blanpain, Maria Sibilia
Format: Article
Language:English
Published: Elsevier 2019-05-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004219301154