A Time-Saving Strategy to Generate Double Maternal Mutants by an Oocyte-Specific Conditional Knockout System in Zebrafish

A Time-Saving Strategy to Generate Double Maternal Mutants by an Oocyte-Specific Conditional Knockout System in Zebrafish

Maternal products are those mRNAs and proteins deposited during oogenesis, which play critical roles in controlling oocyte formation, fertilization, and early embryonic development. However, loss-of-function studies for these maternal factors are still lacking, mainly because of the prolonged period...

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Bibliographic Details
Main Authors: Chong Zhang, Jiaguang Li, Imran Tarique, Yizhuang Zhang, Tong Lu, Jiasheng Wang, Aijun Chen, Fenfen Wen, Zhuoyu Zhang, Yanjun Zhang, Ming Shao
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Biology
Subjects:
maternal factors
oocyte
CRISPR/Cas9
double mutant
early development
zebrafish
Online Access:https://www.mdpi.com/2079-7737/10/8/777

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https://www.mdpi.com/2079-7737/10/8/777

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