Icaritin protects SH-SY5Y cells transfected with TDP-43 by alleviating mitochondrial damage and oxidative stress

Background The aim of this study was to investigate the effect of icaritin (ICT) on TAR DNA-binding protein 43 (TDP-43)-induced neuroblastoma (SH-SY5Y) cell damage and to further explore its underlying mechanisms. Methods To investigate the possible mechanism, TDP-43 was used to induce SH-SY5Y cell...

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Bibliographic Details
Main Authors: Yongjian Zhou, Nanqu Huang, Yuanyuan Li, Zhisheng Ba, Yanjun Zhou, Yong Luo
Format: Article
Language:English
Published: PeerJ Inc. 2021-08-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/11978.pdf