Genome-Wide Association Study of Circadian Rhythmicity in 71,500 UK Biobank Participants and Polygenic Association with Mood InstabilityResearch in context

Background: Circadian rhythms are fundamental to health and are particularly important for mental wellbeing. Disrupted rhythms of rest and activity are recognised as risk factors for major depressive disorder and bipolar disorder. Methods: We conducted a genome-wide association study (GWAS) of low r...

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Bibliographic Details
Main Authors: Amy Ferguson, Laura M. Lyall, Joey Ward, Rona J. Strawbridge, Breda Cullen, Nicholas Graham, Claire L. Niedzwiedz, Keira J.A. Johnston, Daniel MacKay, Stephany M. Biello, Jill P. Pell, Jonathan Cavanagh, Andrew M. McIntosh, Aiden Doherty, Mark E.S. Bailey, Donald M. Lyall, Cathy A. Wyse, Daniel J. Smith
Format: Article
Language:English
Published: Elsevier 2018-09-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396418302925