A humanized mouse model of HPV-associated pathology driven by E7 expression.

Human papillomavirus (HPV) is the causative agent of human cervical cancer and has been associated with oropharyngeal squamous cell carcinoma development. Although prophylactic vaccines have been developed, there is a need to develop new targeted therapies for individuals affected with malignant inf...

Full description

Bibliographic Details
Main Authors: Águeda Buitrago-Pérez, Mariam Hachimi, Marta Dueñas, Belén Lloveras, Almudena Santos, Almudena Holguín, Blanca Duarte, Juan Luis Santiago, Baki Akgül, José L Rodríguez-Peralto, Alan Storey, Catalina Ribas, Fernando Larcher, Marcela del Rio, Jesús M Paramio, Ramón García-Escudero
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22911850/?tool=EBI