omniCLIP: probabilistic identification of protein-RNA interactions from CLIP-seq data

Abstract CLIP-seq methods allow the generation of genome-wide maps of RNA binding protein – RNA interaction sites. However, due to differences between different CLIP-seq assays, existing computational approaches to analyze the data can only be applied to a subset of assays. Here, we present a probab...

Full description

Bibliographic Details
Main Authors: Philipp Drewe-Boss, Hans-Hermann Wessels, Uwe Ohler
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Genome Biology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13059-018-1521-2