Mitochondrial contribution to lipofuscin formation

Mitochondria have been in the focus of oxidative stress and aging research for decades due to their permanent production of ROS during the oxidative phosphorylation. The hypothesis exists that mitochondria are involved in the formation of lipofuscin, an autofluorescent protein aggregate that accumul...

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Bibliographic Details
Main Authors: Jeannette König, Christiane Ott, Martín Hugo, Tobias Jung, Anne-Laure Bulteau, Tilman Grune, Annika Höhn
Format: Article
Language:English
Published: Elsevier 2017-04-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231717300423