High-Resolution Melting Curve Analysis for High-Throughput Genotyping of NOD2/CARD15 Mutations and Distribution of These Mutations in Slovenian Inflammatory Bowel Diseases Patients

Inflammatory bowel diseases (IBD) are usually classified into Crohn's disease (CD) and ulcerative colitis (UC). NOD2/CARD15 was the first identified CD-susceptibility gene and was confirmed as the most potent disease gene in CD pathogenesis. Three NOD2/CARD15 variants, namely two missense polym...

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Bibliographic Details
Main Authors: Mitja Mitrovič, Uroš Potočnik
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.3233/DMA-2011-0783