Pre-mRNA secondary structures influence exon recognition.

The secondary structure of a pre-mRNA influences a number of processing steps including alternative splicing. Since most splicing regulatory proteins bind to single-stranded RNA, the sequestration of RNA into double strands could prevent their binding. Here, we analyzed the secondary structure conte...

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Bibliographic Details
Main Authors: Michael Hiller, Zhaiyi Zhang, Rolf Backofen, Stefan Stamm
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-11-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2077896?pdf=render