Triple Trouble: A Case of Multiple Resistance Mechanisms after First Generation EGFR-TKI in NSCLC

Epidermal growth factor receptor (EGFR)-targeted therapy has become standard of care in advanced stages EGFR-mutant non-small cell lung cancer. Acquired resistance to first-line EGFR-tyrosine kinase inhibitor (TKI) and subsequent disease progression is a common problem and mostly due to a secondary...

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Bibliographic Details
Main Authors: Mike Ralki, Brigitte Maes, Karin Pat, Jokke Wynants, Kristof Cuppens
Format: Article
Language:English
Published: Karger Publishers 2019-08-01
Series:Case Reports in Oncology
Subjects:
Online Access:https://www.karger.com/Article/FullText/502214