XIST lost induces ovarian cancer stem cells to acquire taxol resistance via a KMT2C-dependent way

XIST lost induces ovarian cancer stem cells to acquire taxol resistance via a KMT2C-dependent way

Abstract Background/aims The expression levels of long non-coding RNA XIST are significantly associated with paclitaxel (Pac) sensitivity in ovarian cancer, but the mechanism of action remains unclear. Therefore, this experimental design was based on lncRNA XIST analysis to regulate the effect of XI...

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Bibliographic Details
Main Authors: Ruili Huang, Lijuan Zhu, Yali Zhang
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Cancer Cell International
Subjects:
LncRNA XIST
KMT2C
Ovarian cancer
Tumor stem cells
Proliferation
Online Access:http://link.springer.com/article/10.1186/s12935-020-01500-8

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http://link.springer.com/article/10.1186/s12935-020-01500-8

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