Role of TNF in the altered interaction of dormant Mycobacterium tuberculosis with host macrophages.

Mycobacterium tuberculosis (Mtb) persists within lung granulomas, despite being subjected to diverse stress conditions, including hypoxia. We hypothesized that the response of host phagocytes to Mtb experiencing hypoxia is radically altered and designed in vitro experiment to study this phenomenon....

Full description

Bibliographic Details
Main Authors: Uma S Gautam, Smriti Mehra, Muhammad H Ahsan, Xavier Alvarez, Tianhua Niu, Deepak Kaushal
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3990579?pdf=render