Amide-Type Substrates in the Synthesis of <i>N</i>-Protected 1-Aminomethylphosphonium Salts

Amide-Type Substrates in the Synthesis of <i>N</i>-Protected 1-Aminomethylphosphonium Salts

Herein we describe the development and optimization of a two-step procedure for the synthesis of <i>N</i>-protected 1-aminomethylphosphonium salts from imides, amides, carbamates, or lactams. Our “step-by-step” methodology involves the transformation of amide-type substrates to the corre...

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Bibliographic Details
Main Authors: Dominika Kozicka, Paulina Zieleźny, Karol Erfurt, Jakub Adamek
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Catalysts
Subjects:
imides
amides
phosphonium salts
α-amidoalkylation
α-amidoalkylating agents
Online Access:https://www.mdpi.com/2073-4344/11/5/552

Internet

https://www.mdpi.com/2073-4344/11/5/552

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