Computational prediction of protein aggregation: Advances in proteomics, conformation-specific algorithms and biotechnological applications

Computational prediction of protein aggregation: Advances in proteomics, conformation-specific algorithms and biotechnological applications

Protein aggregation is a widespread phenomenon that stems from the establishment of non-native intermolecular contacts resulting in protein precipitation. Despite its deleterious impact on fitness, protein aggregation is a generic property of polypeptide chains, indissociable from protein structure...

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Bibliographic Details
Main Authors: Jaime Santos, Jordi Pujols, Irantzu Pallarès, Valentín Iglesias, Salvador Ventura
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Protein aggregation
Bioinformatics
Amyloid
Protein structure
Proteomics
Evolution
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037020302919

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http://www.sciencedirect.com/science/article/pii/S2001037020302919

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