Vitamin D Receptor TaqI Polymorphism Is Associated With Reduced Follicle Number in Women Utilizing Assisted Reproductive Technologies

Vitamin D Receptor TaqI Polymorphism Is Associated With Reduced Follicle Number in Women Utilizing Assisted Reproductive Technologies

PurposeCalcitriol, or 1,25-hydroxycholecalciferol, is the active form of vitamin D. It binds and activates vitamin D receptor (VDR). Infertility and defective folliculogenesis have been observed in female vdr-knockout mice; however, whether VDR polymorphisms affect human ovarian responses to control...

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Bibliographic Details
Main Authors: Mila W. Reginatto, Bartira M. Pizarro, Roberto A. Antunes, Ana C. A. Mancebo, Luísa Hoffmann, Pâmela Fernandes, Patrícia Areas, Maria I. Chiamolera, Rosane Silva, Maria do Carmo Borges de Souza, Enrrico Bloise, Tânia M. Ortiga-Carvalho
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Endocrinology
Subjects:
calcitriol
VDR polymorphisms
25(OH)D
TaqI
folliculogenesis
infertility
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2018.00252/full

Internet

https://www.frontiersin.org/article/10.3389/fendo.2018.00252/full

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