NADPH oxidase NOX4 is a glycolytic regulator through mROS-HIF1α axis in thyroid carcinomas

Abstract The function of the NAD(P)H oxidases (NOXs) family member NOX4 is to generate reactive oxygen species (ROS), however, the molecular function of NOX4 has not been fully studied and waiting to be clarified. To elucidate the function of endogenous Nox4 in human thyroid carcinomas, papillomatos...

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Bibliographic Details
Main Authors: Ping Tang, Hao Dang, Jie Huang, Tao Xu, Ping Yuan, Jun Hu, Jian-feng Sheng
Format: Article
Language:English
Published: Nature Publishing Group 2018-10-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-018-34154-8