Effects of neuroactive metabolites of the tryptophan pathway on working memory and cortical thickness in schizophrenia

Effects of neuroactive metabolites of the tryptophan pathway on working memory and cortical thickness in schizophrenia

Abstract A number of tryptophan metabolites known to be neuroactive have been examined for their potential associations with cognitive deficits in schizophrenia. Among these metabolites, kynurenic acid (KYNA), 5-hydroxyindole (5-HI), and quinolinic acid (QUIN) are documented in their diverse effects...

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Main Authors: Junchao Huang, Jinghui Tong, Ping Zhang, Yanfang Zhou, Yimin Cui, Shuping Tan, Zhiren Wang, Fude Yang, Peter Kochunov, Joshua Chiappelli, Baopeng Tian, Li Tian, Yunlong Tan, L. Elliot Hong
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-021-01311-z

Internet

https://doi.org/10.1038/s41398-021-01311-z

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