Muscle-specific adaptations, impaired oxidative capacity and maintenance of contractile function characterize diet-induced obese mouse skeletal muscle.

Muscle-specific adaptations, impaired oxidative capacity and maintenance of contractile function characterize diet-induced obese mouse skeletal muscle.

BACKGROUND:The effects of diet-induced obesity on skeletal muscle function are largely unknown, particularly as it relates to changes in oxidative metabolism and morphology. PRINCIPAL FINDINGS:Compared to control fed mice, mice fed a high fat diet (HFD; 60% kcal: fat) for 8 weeks displayed increased...

Full description

Bibliographic Details
Main Authors: Karin E Shortreed, Matthew P Krause, Julianna H Huang, Dili Dhanani, Jasmin Moradi, Rolando B Ceddia, Thomas J Hawke
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2752162?pdf=render

Internet

http://europepmc.org/articles/PMC2752162?pdf=render

Similar Items