Development of a preliminary in vitro drug screening assay based on a newly established culturing system for pre-adult fifth-stage Onchocerca volvulus worms.

Development of a preliminary in vitro drug screening assay based on a newly established culturing system for pre-adult fifth-stage Onchocerca volvulus worms.

BACKGROUND:The human filarial parasite Onchocerca volvulus is the causative agent of onchocerciasis (river blindness). It causes blindness in 270,000 individuals with an additional 6.5 million suffering from severe skin pathologies. Current international control programs focus on the reduction of mi...

Full description

Bibliographic Details
Main Authors: Denis Voronin, Nancy Tricoche, Shabnam Jawahar, Michael Shlossman, Christina A Bulman, Chelsea Fischer, Michael T Suderman, Judy A Sakanari, Sara Lustigman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC6353222?pdf=render

Internet

http://europepmc.org/articles/PMC6353222?pdf=render

Similar Items