The MARCH family E3 ubiquitin ligase K5 alters monocyte metabolism and proliferation through receptor tyrosine kinase modulation.

The MARCH family E3 ubiquitin ligase K5 alters monocyte metabolism and proliferation through receptor tyrosine kinase modulation.

Kaposi's sarcoma (KS) lesions are complex mixtures of KS-associated herpesvirus (KSHV)-infected spindle and inflammatory cells. In order to survive the host immune responses, KSHV encodes a number of immunomodulatory proteins, including the E3 ubiquitin ligase K5. In exploring the role of this...

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Bibliographic Details
Main Authors: Roshan Karki, Sabine M Lang, Robert E Means
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-04-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3072377?pdf=render

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http://europepmc.org/articles/PMC3072377?pdf=render

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