The Toll-Like Receptor 5 agonist flagellin prevents Non-typeable Haemophilus influenzae-induced infection in cigarette smoke-exposed mice.

The Toll-Like Receptor 5 agonist flagellin prevents Non-typeable Haemophilus influenzae-induced infection in cigarette smoke-exposed mice.

Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality worldwide. The major bacterial cause of COPD exacerbations is non-typeable Haemophilus influenzae (NTHi). 25 to over 80% of cases are associated with NTHi. This susceptibility to infection involves a defective p...

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Bibliographic Details
Main Authors: Magdiel Pérez-Cruz, Bachirou Koné, Rémi Porte, Christophe Carnoy, Julien Tabareau, Pierre Gosset, François Trottein, Jean-Claude Sirard, Muriel Pichavant, Philippe Gosset
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0236216

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https://doi.org/10.1371/journal.pone.0236216

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