Regulation of neuronal differentiation by proteins associated with nuclear bodies.

Nuclear bodies are large sub-nuclear structures composed of RNA and protein molecules. The Survival of Motor Neuron (SMN) protein localizes to Cajal bodies (CBs) and nuclear gems. Diminished cellular concentration of SMN is associated with the neurodegenerative disease Spinal Muscular Atrophy (SMA)....

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Main Authors: Benjamin Förthmann, Jeroen van Bergeijk, Yu-Wei Lee, Verena Lübben, Yvonne Schill, Hella Brinkmann, Andreas Ratzka, Michal K Stachowiak, Michael Hebert, Claudia Grothe, Peter Claus
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3866168?pdf=render