Methylation Status of the SOCS3 Gene Promoter in H2228 Cells and 
EML4–ALK-positive Lung Cancer Tissues

Methylation Status of the SOCS3 Gene Promoter in H2228 Cells and 
EML4–ALK-positive Lung Cancer Tissues

Background and objective The EML4-ALK fusion gene is a newly discovered driver gene of non-small cell lung cancer and exhibits special clinical and pathological features. The JAK-STAT signaling pathway, an important downstream signaling pathway of EML4-ALK, is aberrantly sustained and activated in E...

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Bibliographic Details
Main Authors: Chunlai LIU, Yongwen LI, Yunlong DONG, Hongbing ZHANG, Ying LI, Hongyu LIU, Jun CHEN
Format: Article
Language:zho
Published: Chinese Anti-Cancer Association; Chinese Antituberculosis Association 2016-09-01
Series:Chinese Journal of Lung Cancer
Subjects:
Lung neoplasms
Echinoderm microtubule-associated-protein-like 4 (EML4)
Anaplastic lymphoma kinase (ALK)
Suppressor of cytokine signaling 3 (SOCS3)
DNA methylation
Online Access:http://dx.doi.org/10.3779/j.issn.1009-3419.2016.09.01

Internet

http://dx.doi.org/10.3779/j.issn.1009-3419.2016.09.01

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