Macrophage Activation in the Synovium of Healthy and Osteoarthritic Equine Joints
Synovitis is a major component of osteoarthritis and is driven primarily by macrophages. Synovial macrophages are crucial for joint homeostasis (M2-like phenotype), but induce inflammation (M1-like) when regulatory functions become overwhelmed. Macrophage phenotypes in synovium from osteoarthritic a...
Main Authors: | Bruno C. Menarim, Kiersten H. Gillis, Andrea Oliver, Ying Ngo, Stephen R. Werre, Sarah H. Barrett, Dwayne H. Rodgerson, Linda A. Dahlgren |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2020-11-01
|
Series: | Frontiers in Veterinary Science |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fvets.2020.568756/full |
Similar Items
-
Review: Mesenchymal Stem Cell Therapy in Canine Osteoarthritis Research: “Experientia Docet” (Experience Will Teach Us)
by: Carlien Brondeel, et al.
Published: (2021-05-01) -
The Effect of Training on Adopting Behaviors Preventing from Knee Osteoarthritis Based on Planned Behavior Theory
by: S, et al.
Published: (2015-05-01) -
Comprehensive Analysis of Key Genes, Signaling Pathways and miRNAs in Human Knee Osteoarthritis: Based on Bioinformatics
by: Liang Chang, et al.
Published: (2021-08-01) -
Age-related changes in bone morphometry, densitometry and osteoarthritis in macaques
by: Pomchote, Porrawee
Published: (2015) -
Regulation of Tumor Necrosis Factor-α by Peptide Lv in Bone Marrow Macrophages and Synovium
by: Manabu Mukai, et al.
Published: (2021-07-01)