Smart Hydrogels for the Augmentation of Bone Regeneration by Endogenous Mesenchymal Progenitor Cell Recruitment

Smart Hydrogels for the Augmentation of Bone Regeneration by Endogenous Mesenchymal Progenitor Cell Recruitment

Abstract The treatment of bone defects with recombinant bone morphogenetic protein‐2 (BMP‐2) requires high doses precluding broad clinical application. Here, a bioengineering approach is presented that strongly improves low‐dose BMP‐2‐based bone regeneration by mobilizing healing‐associated mesenchy...

Full description

Bibliographic Details
Main Authors: Philipp S. Lienemann, Queralt Vallmajo‐Martin, Panagiota Papageorgiou, Ulrich Blache, Stéphanie Metzger, Anna‐Sofia Kiveliö, Vincent Milleret, Ana Sala, Sylke Hoehnel, Aline Roch, Raphael Reuten, Manuel Koch, Olaia Naveiras, Franz E. Weber, Wilfried Weber, Matthias P. Lutolf, Martin Ehrbar
Format: Article
Language:English
Published: Wiley 2020-04-01
Series:Advanced Science
Subjects:
bone healing
bone morphogenetic proteins
growth factors
hydrogels
progenitor cells
Online Access:https://doi.org/10.1002/advs.201903395

Internet

https://doi.org/10.1002/advs.201903395

Similar Items